Occurrence and human exposure risk of antibiotic resistance genes in tillage soils of dryland regions: A case study of northern Ningxia Plain, China

doi:10.1016/j.jhazmat.2024.135790

	Occurrence and human exposure risk of antibiotic resistance genes in tillage soils of dryland regions: A case study of northern Ningxia Plain, China
	Sun, Jianbin 1,2,3; Zhang, Dan 1,2,3; Peng, Shuang 1,3,4; Yang, Xiaoqian 1; Hua, Qingqing 1; Wang, Wei 1; Wang, Yiming 1,2,3,5; Lin, Xiangui 1,3
	2024-12-05
发表期刊	JOURNAL OF HAZARDOUS MATERIALS
ISSN	0304-3894
卷号	480
摘要	Agricultural soils are important source and sink of antibiotic resistance genes (ARGs). However, little is known about the fate of ARGs in dryland soils, while its human exposure risks were seriously overlooked. Taking the northern Ningxia Plain as a case, this study explored the occurrence of ARGs and its relationship with mobile genetic elements (MGEs), pathogens, and environmental factors. Furthermore, the concentrations of airborne ARGs by soil wind erosion and the human exposure doses of soil ARGs were evaluated. The results showed the abundances of different regions ranged from 4.0 x 10(5) to 1.6 x 10(6) copies/g. Soil ARGs are driven by MGEs, but multiply impacted by soil properties, nutrition, and bacterial community. Vibrio metschnikovii, Acinetobacter schindleri, and Serratia marcescens are potential pathogenic hosts for ARGs. Further exploration revealed the concentration of ARGs loaded in dust by soil wind erosion reached more than 10(5) copies/m(3), which were even higher than those found in sewage treatment plants and hospitals. Skin contact is the primary route of ARGs exposure, with a maximum dose of 24071.33 copies/kg/d, which is largely attributed to ARGs loaded in dust. This study bridged the gap on ARGs in dryland soils, and provided reference for human exposure risk assessment of soil ARGs.
关键词	Antibiotic resistance genes Dryland soil Pathogenic bacteria Soil wind erosion Exposure risk
其他关键词	ANTIMICROBIAL RESISTANCE ; AIRBORNE BACTERIA ; HEALTH
DOI	10.1016/j.jhazmat.2024.135790
收录类别	SCIE
语种	英语
WOS研究方向	Engineering ; Environmental Sciences & Ecology
WOS类目	Engineering, Environmental ; Environmental Sciences
WOS记录号	WOS:001316263800001
出版者	ELSEVIER
原始文献类型	Article
EISSN	1873-3336
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.library.ouchn.edu.cn/handle/39V7QQFX/171622
专题	国家开放大学江苏分部
通讯作者	Peng, Shuang; Wang, Yiming
作者单位	1.Chinese Acad Sci, Inst Soil Sci, State Key Lab Soil & Sustainable Agr, Nanjing 211135, Peoples R China; 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China; 3.Jiangsu Collaborat Innovat Ctr Solid Organ Waste R, Nanjing 210095, Peoples R China; 4.Jiangsu Open Univ, Coll Environm & Ecol, Nanjing 210017, Peoples R China; 5.Ningxia Univ, Coll Agr, Yinchuan 750021, Peoples R China
通讯作者单位	国家开放大学江苏分部
推荐引用方式 GB/T 7714	Sun, Jianbin,Zhang, Dan,Peng, Shuang,et al. Occurrence and human exposure risk of antibiotic resistance genes in tillage soils of dryland regions: A case study of northern Ningxia Plain, China[J]. JOURNAL OF HAZARDOUS MATERIALS,2024,480.
APA	Sun, Jianbin.,Zhang, Dan.,Peng, Shuang.,Yang, Xiaoqian.,Hua, Qingqing.,...&Lin, Xiangui.(2024).Occurrence and human exposure risk of antibiotic resistance genes in tillage soils of dryland regions: A case study of northern Ningxia Plain, China.JOURNAL OF HAZARDOUS MATERIALS,480.
MLA	Sun, Jianbin,et al."Occurrence and human exposure risk of antibiotic resistance genes in tillage soils of dryland regions: A case study of northern Ningxia Plain, China".JOURNAL OF HAZARDOUS MATERIALS 480(2024).