Overview of the preparation method, structure and function, and application of natural peptides and polypeptides

doi:10.1016/j.biopha.2022.113493

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	Overview of the preparation method, structure and function, and application of natural peptides and polypeptides
	Feng, Li 1; Wang, Yue 2; Yang, Jian 5; Sun, Yi-fan 6; Li, Yi-wei 2; Ye, Zi-hong 2; Lin, Han-bin 3,4; Yang, Ke 2,3
	2022-09
发表期刊	BIOMEDICINE & PHARMACOTHERAPY;
ISSN	0753-3322
卷号	153
摘要	Natural polypeptides, a kind of molecular polymer with obvious biological activity, are widely existing in nature. They participate in various physiological activities of living organisms and play an important role in promoting human health. They are also widely applied in medicine, food, and cosmetic industries. By searching literature from Pubmed, Google Scholar, Web of Science, Springer Link and Elsevier, this work presents an overview of the preparation methods, the relationship between structure and function, and the application of natural poly -peptides. The preparation methods mainly include solvent extraction, enzymatic decomposition, microbiological fermentation, chemical synthesis, genetic engineering recombination, and using cell free system. Natural poly-peptide's physiological function mainly includes antioxidative, antibacterial, antihypertensive. This review could provide scientific basis for the research and development of natural polypeptide.
关键词	Natural peptide and polypeptide Preparation Structure-activity relationship Application
DOI	10.1016/j.biopha.2022.113493
收录类别	SCIE
语种	英语
资助项目	National Natural Science Founda-tion of China [81803761, 82100391];China Postdoctoral Science Foundation [2019M652144, 2060302];High-level new R&D institute of Department of Science and Technology of Guangdong Province [2019B090904008];High-level Innovative Research Institute of Department of Science and Technology of Guang-dong Province [2021B0909050003];Shandong Provincial Key Research and Development Program (Major Technological Innovation Project) [2021CXGC010508];Leading Talents in Science and Technology Innovation of Ten Thousand Talents Program in Zhejiang Province [2019R52018];
WOS研究方向	Research & Experimental Medicine ; Pharmacology & Pharmacy
WOS类目	Medicine, Research & Experimental ; Pharmacology & Pharmacy
WOS记录号	WOS:000838910900006
出版者	ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
原始文献类型	Review
EISSN	1950-6007
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.library.ouchn.edu.cn/handle/39V7QQFX/27360
通讯作者	Lin, Han-bin; Yang, Ke
作者单位	1.Open Univ China, Coll Agroforestry & Med, Beijing 100039, Peoples R China; 2.China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspection & Qua, Hangzhou 310018, Peoples R China; 3.Chinese Acad Sci, Zhongshan Inst Drug Discovery, SIMM, Zhongshan 528400, Guangdong, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China; 5.China Acad Chinese Med Sci, Natl Resource Ctr Chinese Mat Med, State Key Lab Breeding Base Dao di Herbs, Beijing 100700, Peoples R China; 6.Chinese Acad Med Sci, Inst Med Informat, Beijing 100020, Peoples R China
推荐引用方式 GB/T 7714	Feng, Li,Wang, Yue,Yang, Jian,et al. Overview of the preparation method, structure and function, and application of natural peptides and polypeptides[J]. BIOMEDICINE & PHARMACOTHERAPY;,2022,153.
APA	Feng, Li.,Wang, Yue.,Yang, Jian.,Sun, Yi-fan.,Li, Yi-wei.,...&Yang, Ke.(2022).Overview of the preparation method, structure and function, and application of natural peptides and polypeptides.BIOMEDICINE & PHARMACOTHERAPY;,153.
MLA	Feng, Li,et al."Overview of the preparation method, structure and function, and application of natural peptides and polypeptides".BIOMEDICINE & PHARMACOTHERAPY; 153(2022).